9. Pathogenesis 3
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Description
MMPS — MATRIX METALO PROTEINASES Most important proteinase involved in destruction of periodontal tissue EG: MMP – 8, MMP – 13 GINGIVAL CREVICULAR FLUID GCF has most abundance of...
show moreMost important proteinase involved in destruction of
periodontal tissue
EG: MMP – 8, MMP – 13
GINGIVAL CREVICULAR FLUID
GCF has most abundance of IgG
CONTAINS
o Components of CT
o Epithelium
o Inflammatory cells
o Serum
o Microbial flora living there in the sulcus
More neutrophils to defend the gingiva.
Most drug concentration
o 1st tetracycline/doxycycline
o 2nd metronidazole
DOXYCYCLINE – similar to tetracycline
QN Tetracycline cause brownish discoloration in all teeth & appear yellowish with UV light
Pedo —20mg
Therapeutic value — 100mg /day (Antibacterial dose)
Sub antimicrobial dose = 20mg — bacteriostatic at GCF
Information
Author | Dr.Mayakha Mariam |
Website | - |
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