Common diabetes drug slows growth of normal cells carrying cancer mutation
Sep 10, 2024 ·
6m 42s
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Description
A common diabetes medication, metformin, slows the growth of precancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study. Researchers from the Wellcome Sanger Institute...
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A common diabetes medication, metformin, slows the growth of precancerous cells in the oesophagus while some metabolic conditions accelerate it, suggests a new study.
Researchers from the Wellcome Sanger Institute discovered that metformin reduced the growth of potentially cancerous cells both in mice and laboratory experiments. The team also found that metabolic conditions such as diabetes and obesity could enhance the growth advantage of these altered cells in human samples.
The findings, recently published in Nature Genetics, highlight the potential role of metformin and overall metabolic health in managing squamous oesophageal cancer risk. Researchers suggest the drug may be beneficial beyond its role in diabetes, though more research is needed.
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Researchers from the Wellcome Sanger Institute discovered that metformin reduced the growth of potentially cancerous cells both in mice and laboratory experiments. The team also found that metabolic conditions such as diabetes and obesity could enhance the growth advantage of these altered cells in human samples.
The findings, recently published in Nature Genetics, highlight the potential role of metformin and overall metabolic health in managing squamous oesophageal cancer risk. Researchers suggest the drug may be beneficial beyond its role in diabetes, though more research is needed.
Information
| Author | Wellcome Sanger Institute |
| Organization | Wellcome Sanger Institute |
| Website | - |
| Tags |
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