Over the past 24 hours, several key developments and recommendations have emerged for fantasy football managers as they prepare for Week 5 of the 2024 NFL season.

### Quarterback Targets
For those in need of a quarterback, Sam Darnold of the Minnesota Vikings has been highlighted as a top waiver-wire pickup. Darnold's recent performance makes him an attractive option for fantasy teams looking to bolster their QB position.

### Running Backs
Several running backs have gained attention due to their recent performances and changing roles within their teams.

- **Bucky Irving** of the Tampa Bay Buccaneers continues to outperform starter Rachaad White, seeing a season-high five red-zone attempts in Week 4. Irving is a must-roster player, even if he won't fully take over the backfield without an injury to White.
- **Isiah Hunt** of the Kansas City Chiefs is another key pickup, having taken over Carson Steele's role. However, his role could be impacted by the potential return of Clyde Edwards-Helaire.
- **Tank Bigsby** of the Jacksonville Jaguars is also worth considering, though his availability and FAAB bids are relatively high.

### Wide Receivers
Wide receiver pickups are crucial for adding depth and scoring potential to fantasy teams.

- **Dontayvion Wicks** of the Green Bay Packers had a breakout game, catching five passes for 78 yards and two touchdowns. With a favorable matchup against the Los Angeles Rams in Week 5, Wicks is a highly recommended pickup.
- **Josh Downs** of the Indianapolis Colts is another standout, having caught 8-of-9 passes for 82 yards and a touchdown in his second game of the season. Downs faces a Jacksonville Jaguars defense that has been vulnerable to wide receivers.
- **Tre Tucker** of the Las Vegas Raiders has seen increased target shares with Davante Adams out and could continue to see a more featured role.

### Tight Ends and Kickers
For tight end and kicker positions, which often see volatility, a few names stand out:

- **Tyler Conklin** of the Minnesota Vikings has shown consistent target shares and could be a viable option for tight end-needy teams.
- **Austin Seibert** and **Chase McLaughlin** are recommended kickers due to their favorable matchups and the defensive weaknesses of their opponents.

### Defense/Special Teams
Defensive units can also make a significant impact on fantasy scores.

- The **Seattle Seahawks D/ST** against the New York Giants and the **New England Patriots D/ST** against the Miami Dolphins are highlighted as strong streaming options due to the weaknesses of their opponents' offenses.

These recommendations should help fantasy football managers make informed decisions as they navigate the waiver wire and prepare for Week 5 of the 2024 NFL season.