Over the past 24 hours, several key developments have impacted fantasy football lineups for Week 4 of the 2024 NFL season. Here are the most significant updates:

## Injury Updates

- **Deebo Samuel**: Despite a calf injury, Samuel plans to play against the Patriots. However, his usage is considered somewhat risky, and he is expected to be a top 20 option if active.
- **Joe Mixon**: Mixon's status is uncertain due to an ankle injury, making him a gametime decision. If he plays, it's advised to approach with caution, and if he's inactive, Cam Akers could become a viable option.
- **Chris Olave**: Olave is questionable with a hamstring injury and is also a gametime decision. There is concern that the injury could be aggravated during the game, so it's recommended to have a fully healthy alternative ready.
- **Alvin Kamara**: Kamara is expected to play despite hip and ribs injuries. His injuries are seen as minor, and he can be used as normal.
- **Keenan Allen**: Allen is questionable with a heel injury but is expected to play after practicing on Friday.
- **Jordan Love**: Love is expected to play despite not having a full practice since injuring his knee. However, there is some concern about his full health, and it's suggested to prefer a fully healthy quarterback if possible.

## Player Availability

- **Tank Dell** and **DeVonta Smith** are out for this week's games due to a chest injury and a concussion, respectively.
- **Davante Adams** will miss the game with a hamstring injury and may be out for more than one week.
- **Rachaad White** and **Bucky Irving** of the Tampa Bay Buccaneers are expected to be active, with White preferred in PPR formats and Irving in standard formats.

## Fantasy Implications

- **Jaden Reed**: With Jordan Love expected to play, Reed's fantasy value increases significantly, having averaged 19.9 fantasy points per game over his last nine games with Love as his quarterback.
- **Justin Herbert**: Despite being expected to play, Herbert is not recommended for fantasy lineups due to the run-heavy scheme under Jim Harbaugh.
- **Ken Walker**: Walker is set to return from injury and face the Lions, but his trustworthiness in fantasy lineups is questionable in his first game back.

## General Advice

- For players with similar rankings, it is generally advised to favor the fully healthy option to minimize risk.
- Keep an eye on last-minute updates and inactives, as several key players' statuses will be decided close to kickoff.

These updates are crucial for making informed decisions about your fantasy football lineups for Week 4. Stay tuned for any further developments as the day progresses.