Guinea pig, which is suggested as domesticated descendants of a closely related species of cavy, is a kind of rodent that does not exist naturally in the wild. It is one of the earliest species that has been applied in the field of research and investigation for more than 20 decades. However, as the genetic research of guinea pig (such as guinea pig antibody) has fallen behind during the early 20th century, it becomes less popular than mice and rats in a variety of research (such as humanized mice antibody). Even though, it is still an ideal source to generate antibodies for extreme allergic reactions or anaphylaxis research. It is also treated as an important model for the study of various infectious diseases, such as tuberculosis and diphtheria. https://www.creative-biolabs.com/blog/index.php/creative-biolabs-makes-breakthrough-in-guinea-pig-monoclonal-antibody-production-with-hybridoma-technology/