The architecture of disease
Oct 8, 2024 ·
11m 26s
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Description
Our blog story features some of the people behind the cutting-edge cancer research at the Sanger Institute. With genomic techniques now able to uncover the DNA sequence and structure in...
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Our blog story features some of the people behind the cutting-edge cancer research at the Sanger Institute. With genomic techniques now able to uncover the DNA sequence and structure in millions individual cells, they are uncovering the genetic architecture of disease.
Finding the causes of cancer has been a long-standing goal for many researchers at the Wellcome Sanger Institute. Armed with the latest DNA sequencing technologies, there are a variety of approaches to pinpointing the genetic mutations that are relevant for ageing, disease, or those that could be drug targets. Whichever route is taken, or whichever question is looked at, the data are noisy and complex. Analysis may involve sifting and processing terabytes of genomic data, encompassing millions of genetic variations across thousands of samples. In this story we explore some of the work of staff aiming to understand the molecular underpinnings of cancer and the genetic architectures of our cells.
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Finding the causes of cancer has been a long-standing goal for many researchers at the Wellcome Sanger Institute. Armed with the latest DNA sequencing technologies, there are a variety of approaches to pinpointing the genetic mutations that are relevant for ageing, disease, or those that could be drug targets. Whichever route is taken, or whichever question is looked at, the data are noisy and complex. Analysis may involve sifting and processing terabytes of genomic data, encompassing millions of genetic variations across thousands of samples. In this story we explore some of the work of staff aiming to understand the molecular underpinnings of cancer and the genetic architectures of our cells.
Information
| Author | Wellcome Sanger Institute |
| Organization | Wellcome Sanger Institute |
| Website | - |
| Tags |
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