Homology modeling, one of the most commonly used antibody modeling methods of which the services provided adopts the 3-D antibody protein structures with alike sequences as a sample, and based on which produce a structure combined with the AA differences between the sample and the modeled one. Homology modeling works very well when it is predicting the structure of the Fv region framework, because of the extensively conserved fold of antibodies. Instruction can be reached at https://www.creative-biolabs.com/preciab/antibody-structure-determination.htm.